Cancer Cell Line Encyclopedia Rna Seq

Please see below for a partial list of resources or refer to the list of cancer related data software and tools.

Cancer cell line encyclopedia rna seq. C tissue specific circrna profile across cancer lineages. Additionally wes data for 326 cell lines available from gdc were also obtained and variants were identified. Ccle cancer cell line encyclopedia cclf cancer cell line factory drug repurposing hub prism. 2020 the broad institute of mit harvard.

Global expression landscape of circrnas across cancer cell lines. Rna seq of 934 human cancer cell lines from the cancer cell line encyclopedia rna seq mrna baseline. B violin plot shows number of circrnas identified in cancer lineages with at least 10 cancer cell lines. You may have been redirected here from the broad cancer program resource gateway which is no longer active.

The ccle cancer cell line encyclopedia project is a collaboration between the broad institute and the novartis institutes for biomedical research and its genomics institute of the novartis research foundation to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models to develop integrated computational analyses that link distinct pharmacologic vulnerabilities to genomic patterns and to translate cell line integrative genomics into cancer. May 15 2019. Contributor s gray jw heiser lm. The original cancer cell line encyclopedia ccle is expanded with deeper characterization of over 1 000 cell lines including genomic transcriptomic and proteomic data and integration with.

56 breast cancer cell lines were profiled to identify patterns of gene expression associated with subtype and response to therapeutic compounds. A combination of four computational pipelines to identify circrnas in cancer cell line encyclopedia ccle rna seq data. Project information box is displayed n3. Rna seq data for 934 cell lines available from the nci gdc legacy portal https portal gdc cancer gov were downloaded and bam files were processed to call variants using an in house pipeline described earlier in the methods section.

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